Epocrates, Inc. Files Registration Statement for Proposed Initial Public Offering

San Mateo, Calif., July 16, 2010

Epocrates, Inc., a leading provider of mobile drug reference tools and interactive services to healthcare professionals and the healthcare industry, today announced it has filed a registration statement on Form S-1 with the U.S. Securities and Exchange Commission relating to the proposed initial public offering of its common stock.

J.P. Morgan Securities Inc. and Piper Jaffray & Co. are serving as joint book-running managers for the proposed offering. William Blair & Company, L.L.C. and JMP Securities LLC are acting as co-managers. The number of shares to be sold and the price range for the proposed offering have not yet been determined.

A registration statement relating to Epocrates’ securities has been filed with the Securities and Exchange Commission, but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time that the registration statement becomes effective. This news release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

The proposed offering will be made only by means of a prospectus. Once the prospectus is available, a copy may be obtained from J.P. Morgan Securities Inc., c/o Broadridge Financial Solutions, 1155 Long Island Ave, Edgewood, NY, 11717, or by calling 1-866-803-9204, or from Piper Jaffray & Co., 800 Nicollet Mall, Suite 800, Minneapolis, MN 55402, or by calling 1-800-747-3924 or sending an email to prospectus@pjc.com.

Media Contact

Holly Spring
athenahealth, Inc. (Media)
media@athenahealth.com
617-402-1631

Dana Quattrochi
athenahealth, Inc. (Investors)
investorrelations@athenahealth.com
617-402-1329

April Marks
Epocrates, Inc. (Media)
pr@epocrates.com
650-520-2413