By vgreene, 19 January, 2021 There is no contraindication precaution to vaccination for pts w hx of allergies that are unrelated to components of the mRNA vaccines other vaccines injectable therapies or polysorbate This includes allergies to PO med incl the PO equivalents of injectab
By vgreene, 19 January, 2021 In Pfizer BioNTech clinical trials potential allergic rxns occurred in 0 63 of vaccine recipients vs 0 51 of placebo In the Moderna trials the rates were 1 5 of vaccine recipients vs 1 1 of placebo2
By vgreene, 19 January, 2021 Hx of any immediate allergic rxn to any other vaccine injectable tx ie IM IV or SC vaccines or therapies excluding allergy shots but NOT related to mRNA vaccine components or polysorbate as these are contraindications
By vgreene, 19 January, 2021 Moderate severe acute illness Action Perform risk assessment consider potential deferral of vaccination observe for 15min if decision to vaccinate
By vgreene, 19 January, 2021 Note Previous hx of COVID 19 symptomatic or asymptomatic isn t a contraindication to vaccination although CDC recommends that symptomatic pts defer vaccination until they are recovered out of isolation
By vgreene, 19 January, 2021 Note Individuals w an immediate allergic rxn to the 1st dose of an mRNA vaccine shouldn t receive additional doses of either mRNA vaccine Providers should try to determine whether rxns are immediate allergic rxns or other types of common rxns vasovagal po
By vgreene, 19 January, 2021 Hx of immediate allergic rxn of any severity to polysorbate due to potential cross reactivity w PEG Action Don t vaccinate unless evaluated cleared by allergist immunologist and vaccine can be given w 30 min of observation in a setting w advanced medical
By vgreene, 19 January, 2021 Hx of immediate allergic rxn defined as any hypersensitivity related s sx eg urticaria angioedema resp distress such as wheezing stridor w in 4h of administration of a vaccine or medication of any severity to a previous dose of an mRNA vaccine or any of i
By vgreene, 19 January, 2021 Hx of severe allergic rxn eg anaphylaxis after a previous dose of an mRNA COVID 19 vaccine or any of its components Action Don t vaccinate
