By vgreene, 19 October, 2020 If breakthrough N V re eval emetic risk dz status concurrent illnesses and meds ensure optimal antiemetic regimen is being administered 2
By vgreene, 19 October, 2020 Multiple agents, perhaps in alternating schedules or routes, may be needed<sup>1</sup>
By vgreene, 19 October, 2020 Give additional agent from different drug class; some pts may require several agents w/ different mechanisms of action<sup>1</sup>
By vgreene, 19 October, 2020 If breakthrough N/V, re-eval emetic risk, dz status, concurrent illnesses, and meds; ensure optimal antiemetic regimen is being administered<sup>2</sup>
By vgreene, 19 October, 2020 Antiemetics are most effective when used prophylactically Use maximally effective antiemetics as 1st line tx rather than withholding them for later use 3
By vgreene, 19 October, 2020 Data from two phase II studies support multiday dosing of netupitant palonosetron in association w BEAM FEAM conditioning regimens prior to hematopoietic cell transplant An open label RCT also supports multiday dosing of fosaprepitant Studies on repeat do
