By switaschek, 6 July, 2020 Consider ULT w/ 1st flare if: age 8mg/dL per EULAR, >9mg/dL per ACR), and/or comorbidity (renal impairment, HTN, ischemic heart dz, CHF)3
By switaschek, 6 July, 2020 Initiate ULT if any tophi, joint destruction on radiography, ≥2 flares/yr,2,3 or renal stones3
By vgreene, 6 July, 2020 The Janus Kinase 1/2 Inhibitor Ruxolitinib in COVID-19 With Severe Systemic Hyperinflammation; <a href=https://www.nature.com/articles/s41375-020-0891-0><b><u>access full-text <i>Leukemia</i> article</u></b></a>
By vgreene, 6 July, 2020 Anakinra for Severe Forms of COVID-19: A Cohort Study; full-text Lancet Rheumatol article
By switaschek, 6 July, 2020 If pt unable to tolerate PO, use steroid (IM, IA) over IL-1 inhibitor or ACTH2
By switaschek, 6 July, 2020 Consider low-dose colchicine + anti-inflammatory (NSAID, steroid), per EULAR3