By vgreene, 24 April, 2020 First Case of 2019 Novel Coronavirus in the United States; full-text N Engl J Med article
By vgreene, 24 April, 2020 Efficacy of Hydroxychloroquine in Patients With COVID-19: Results of a Randomized Clinical Trial; pre-print medRxiv article
By vgreene, 24 April, 2020 A Pilot Study of Hydroxychloroquine in Treatment of Patients With Common Coronavirus Disease-19 (COVID-19); full-text J Zhejiang Univ article
By vgreene, 24 April, 2020 Hydroxychloroquine Versus COVID-19: A Rapid Systematic Review and Meta-Analysis
By vgreene, 24 April, 2020 Study considerations: quality of included studies; varied dosing regimens and concomitant AZ; significant heterogeneity btwn studies
By vgreene, 24 April, 2020 Observational studies: sample size ranged from 11 to 1,061 (1,152 pts in total); 75% pts discharged; 3% pts admitted to ICU; 1% pts died; viral clearance in 61% pts; CT scan improvement in 59%
By vgreene, 24 April, 2020 Comparative trials: sample size ranged from 30 to 62 (128 pts in total); no difference in risk ratios btwn HCQ and control groups; CT scan improvement 59% of HCQ group vs 52% of control group; viral clearance in 76% of HCQ group vs 57% of control group; m
By vgreene, 24 April, 2020 Meta-analysis of 6 studies, incl 3 comparative trials, 3 observational studies; all pts received SOC
By vgreene, 24 April, 2020 Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized With Covid-19