By vgreene, 23 March, 2020 Pedi sx may be milder than in adults;1,2 infant case reports, though few, describe mild dz.1 Atypical presentations may be seen in immunosuppressed pts1
By vgreene, 23 March, 2020 Sx: fever, cough (w/ or w/o sputum1), congestion, rhinorrhea, GI sx (vomiting, diarrhea), may occur,2 as well as fatigue, anorexia, malaise, myalgia, dyspnea, sore throat, HA.1 Cough, fever are main sx, per WHO; co-infection w/ other illness possible1
By vgreene, 23 March, 2020 Determine disposition based on sx isolate implement prevention control measures report cases persons under investigation to health dept 1
By vgreene, 23 March, 2020 Use supportive care for home pts, eg, antipyretics3 (NSAIDs not contraindicated, per FDA4). Avoid steroids,3 unless required for other indications (eg, COPD exac);1 weigh benefit/harm of antenatal steroids if pregnant at risk for preterm labor
By vgreene, 23 March, 2020 No drugs are FDA-approved for post-exposure prophylaxis or treatment, though some drugs are being trialed for treatment or given for compassion use1
By vgreene, 23 March, 2020 Severe sx. Pneumonia signs (fever, cough, dyspnea, rapid breathing plus 1+ of these: RR >30, severe resp distress, SpO2
By vgreene, 23 March, 2020 Mildly ill stable pt (incl no signs of pneumonia/hypoxia).2 If isolating at home: Educate about when to seek care (eg, trouble breathing, persistent chest pain/pressure, new confusion, unable to awaken, blue lips/face).1 Pts who are older, have underlying
By vgreene, 23 March, 2020 Virus test symptomatic pts those w close contact w in 6 ft for 15 total min w known case Coinfections may occur1
By vgreene, 23 March, 2020 Imaging findings. Chest CT: bilateral involvement common, areas of consolidation, ground glass opacities; may be NL; CXR/CT alone not recommended for COVID-19 dx1
By vgreene, 23 March, 2020 Common lab findings: lymphopenia (83% inpts), neutrophilia, ↑ALT, AST, ↑LDH, ↑CRP, ↑ferritin1