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By vgreene, 22 June, 2017

Rescreen interval guidance varies by age and PSA level per NCCN 18 if African American consider annual vs every other yr screening d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per N

By vgreene, 21 June, 2017

If African American reasonable to begin discussing PSA screening several yrs earlier than Caucasian pts d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per NCCN13

By vgreene, 21 June, 2017

If African American reasonable to begin discussing PSA screening several yrs earlier than Caucasian pts d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per NCCN11

By vgreene, 21 June, 2017

If known suspected BRCA1 2 refer to cancer genetics specialist if germline BRCA1 2 mutation consider initiating shared decision making about PSA screening at age 40 12 13 Rescreen interval guidance varies by age PSA level per ACP 14 NCCN 15 if African Ame

By vgreene, 16 June, 2017

Centers for Disease Control and Prevention

By vgreene, 16 June, 2017

Centers for Disease Control and Prevention

By vgreene, 16 June, 2017

(BMJ)—A 40-yo woman (gravida 2, para 2) presented 9 days postpartum w/ a 4-day hx of itchy rash that started on her limbs and progressed to her trunk, abdomen, and back. No meds. Exam: tense, fluid-filled blisters on limbs (palms/soles spared), w/ diffuse erythematous plaques on torso. Nikolsky sign neg. What is the dx?

Impetigo herpetiformis

Erythema multiforme

Pemphigoid gestationis

Polymorphic eruption of pregnancy

Epidermolysis bullosa

You are correct. Bx confirmed the typical clinical picture of pemphigoid gestationis, an autoimmune condition thought to be caused by an atypical expression of major histocompatibility class II antigens in the placenta. Pemphigoid gestationis was previously known as herpes gestationis but bears no affiliation w/ the herpes virus. Systemic steroids are the mainstay of tx; antihistamines are used for pruritus. This pt was weaned off steroids over 4wk, w/ full recovery.

BMJ 2017;356:j968

CDC Disclaimer

Rescreen interval guidance varies by age and PSA level per NCCN 18 if African American consider annual vs every other yr screening d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per N

If African American reasonable to begin discussing PSA screening several yrs earlier than Caucasian pts d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per NCCN13

If African American reasonable to begin discussing PSA screening several yrs earlier than Caucasian pts d t greater risk of developing preclinical prostate CA and higher likelihood that a preclinical tumor will metastasize per NCCN11

If known suspected BRCA1 2 refer to cancer genetics specialist if germline BRCA1 2 mutation consider initiating shared decision making about PSA screening at age 40 12 13 Rescreen interval guidance varies by age PSA level per ACP 14 NCCN 15 if African Ame

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