By vgreene, 3 August, 2016 If high bleeding-risk surgery1 planned: Obtain anticoagulation expert input; if also on antiplatelet tx, manage based on agent2
By vgreene, 3 August, 2016 If also on antiplatelet tx, collaborate w/ surgical team, based on particular drug6
By vgreene, 3 August, 2016 If high bleeding-risk surgery1 planned: Hold edoxaban2,3 & delay reinitiation ≥48h up to 30 days post-procedure;4 consider anti-Xa assay; LMWH bridging not indicated; consult expert if VTE event was recent; warning w/ epidural catheters/neuraxial anesthes
By vgreene, 3 August, 2016 Avoid DOACs w/ epidural catheters or neuraxial anesthesia due to bleeding risk
By vgreene, 3 August, 2016 Contact proceduralist/surgeon for specific indications/questions in individual pt clinical scenarios
By vgreene, 3 August, 2016 Consider anti-Xa assay if available immediately pre-op to ensure complete drug elimination