By vgreene, 28 October, 2021 Effect of Early Treatment With Fluvoxamine on Risk of Emergency Care and Hospitalisation Among Patients With COVID 19 The TOGETHER Randomised Platform Clinical Trial access Lancet Global Health article
By vgreene, 28 October, 2021 Primary endpoint of time to viral suppression shorter w CQ difference 6 days higher rate of viral clearance w CQ vs controls by day 10 96 vs 91 and by day 14 80 vs 57 duration of fever shorter w CQ no difference in LOS similar rates of ADRs in both groups
By vgreene, 28 October, 2021 Multicenter prospective observational study 197 hospitalized pts mean age 44y 91 moderate dz w confirmed SARS CoV 2 received CQ 500 mg qd or bid for up to 10 days 176 historical controls mean age 46y received other antiviral tx time btwn sx onset and tx s