By hgreaney@athen…, 17 September, 2021 Use fidaxomicin over vancomycin in adults per IDSA 1 both are options per ACG but not in pregnancy breastfeeding 2 or children3
By hgreaney@athen…, 17 September, 2021 D c precipitating antibiotic fidaxomicin now preferred in adults by IDSA but vancomycin remains an option consider bezlotoxumab if CDI recurred w in 6mo of last episode in certain other pts consider FMT in IBD pts
By vgreene, 16 September, 2021 As of October 21 2021 bamlanivimab etesevimab are authorized for use in all U S states territories and jurisdictions FDA site
By vgreene, 16 September, 2021 REGEN COV distribution currently halted due to high frequency of non susceptible variants
By vgreene, 16 September, 2021 Convalescent Plasma Antibody Levels and the Risk of Death From Covid 19 access N Engl J Med article
By vgreene, 16 September, 2021 Study considerations multicenter randomized but open label pt antibody profile unavailable each standardized log incr in neutralization or antibody dependent cellular cytotoxicity independently reduced the potential harmful effect of plasma
By vgreene, 16 September, 2021 KEY FINDINGS convalescent plasma didn t reduce intubation risk or 30 day mortality significantly higher frequency of serious ADRs w convalescent plasma vs SOC