By hgreaney@athen…, 16 September, 2021 Avoid antimotility agents in untreated CDI but they can be used safely on an as needed basis after anti CDI tx initiated2
By hgreaney@athen…, 16 September, 2021 Consider adding bezlotoxumab to SOC abx in adults 7 per ACG reserve for pts 65 yo8
By hgreaney@athen…, 16 September, 2021 If using vancomycin consider tapered pulsed dosing regimen in setting of recurrent CDI in adults 6 standard dosing preferred in all children w severe CDI3
By hgreaney@athen…, 16 September, 2021 In IBD vancomycin preferred AGA 10 days ACG 14 days 2 4 though AGA suggests fidaxomicin as option5
By hgreaney@athen…, 16 September, 2021 Use fidaxomicin over vancomycin in adults per IDSA 1 both are options per ACG but not in pregnancy breastfeeding 2 or children3
By hgreaney@athen…, 16 September, 2021 D c precipitating antibiotic fidaxomicin now preferred in adults by IDSA but vancomycin remains an option additional tx may be considered
By vgreene, 16 September, 2021 If logistical constraints or limited availability NIH recommends prioritization of use of monoclonal antibodies
