Guideline Resources
Adult Depression Dx/Tx | APA, ACP, VA/DoD, ICSI Guideline Synthesis
Key Points
Mild/Mod Major Depressive Disorder: Offer psychotherapy or 2nd-gen antidepressant (SGA) as initial 1st-line tx; evidence doesn’t favor any given psychotherapy type or particular drug among recommended choices. Severe MDD: Refer to mental health specialist; ECT has ↑response/remission rates vs antidepressant tx. Depression prevalence: 4x more common among US adults during COVID-19 pandemic vs 2019.
Choose Patient Type
Peer reviewed & based on multiple guidelines/recommendations from specialty societies/government agencies.
Epocrates Guideline Synopsis Last Update: Jul 18, 2024
Publication Year:
2024
Source:
epocrates
Abbreviations
ACT acceptance & commitment therapy
BA/BT behavioral therapy/behavioral activation
BDI Beck Depression Inventory
CAM complementary & alternative medicine
CBT cognitive behavioral therapy
d/c discontinue, discontinuation
DBS deep brain stimulation
ECT electroconvulsive therapy
EMDR eye movement desensitization and reprocessing
IPT interpersonal therapy
HAM-D Hamilton Rating Scale for Depression
MAOI monoamine oxidase inhibitor
MCBT mindfulness-based cognitive therapy
MDD major depressive disorder
MDMA methylenedioxymethamphetamine
MINI Mini International Neurospsychiatric Interview
MST magnetic seizure therapy
PHQ-2 Patient Health Questionnaire-2
PHQ-9 Patient Health Questionnaire-9
PST problem-solving therapy
QID-SR Quick Inventory of Depressive Symptomatology Self-Report
SCID-I Structural Clinical Interview DSM-IV Axis-I Disorders
SGA second-generation antidepressant
SNRI serotonin-norepinephrine reuptake inhibitor
SSRI selective serotonin reuptake inhibitor
SUD substance use disorder
TCA tricyclic antidepressant
VNS/DBS vagus nerve stimulation/deep brain stimulation
VNS/rTMS vagus nerve stimulation/repetitive transcranial magnetic stimulation