Highlights & Basics
- Group B streptococcal infection is the most common cause of early, severe infection in newborns.
- It is also a cause of infection in pregnancy, people with diabetes, immunocompromised people, and older adults.
- Presentation depends on the age of the patient and the underlying risk factor.
- Diagnosis is confirmed by isolation of group B streptococci (GBS) from usually sterile body fluid.
- Targeted antibiotic therapy is the mainstay of therapy in patients with demonstrated GBS infection.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Citations
American Academy of Pediatrics. Group B streptococcal infections. In: Committee on Infectious Diseases, American Academy of Pediatrics, Kimberlin DW, Barnett ED, et al. Red book: 2021-2024 report of the Committee on Infectious Diseases. 32nd ed. Elk Grove Village, IL: AAP; 2021:707-13.
The American College of Obstetricians and Gynecologists. Prevention of group B streptococcal early-onset disease in newborns: ACOG Committee Opinion Summary, Number 797. Obstet Gynecol. 2020 Feb;135(2):489-92.[Abstract][Full Text]
National Center for Health Statistics. Active bacterial core surveillance (ABCs) report: emerging infections program network - group B streptococcus, 2018 [internet publication].[Full Text]
Royal College of Obstetricians and Gynaecologists. The prevention of early onset neonatal group B streptococcal disease. Green-top guideline no. 36. Sep 2017 [internet publication].[Abstract][Full Text]
Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database Syst Rev. 2014 Jun 10;(6):CD007467.[Abstract][Full Text]
Puopolo KM, Lynfield R, Cummings JJ, et al. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019 Aug;144(2):e20191881.[Abstract][Full Text]
American Society for Microbiology. Guidelines for the detection and identification of group B streptococcus. 29 July 2021 [internet publication].[Full Text]
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