Lomotil

Adult Dosing .

Dosage forms:  TAB: 2.5 mg/0.025 mg

diarrhea, adjunct tx

[1-2 tabs PO bid-qid prn]

Start: 2 tabs PO qid; Max: 8 tabs/day; Info: reduce dose when sx controlled; D/C after 10 days if no improvement

renal dosing

[see below]

renal impairment: not defined; Info: caution advised in advanced hepatorenal dz

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised; obstructive jaundice: contraindicated

Peds Dosing .

Dosage forms:  TAB: 2.5 mg/0.025 mg

Dosage Forms Discontinued in US

[oral solution not avail. as brand; see generic]

diarrhea, adjunct tx

[6-12 yo (off-label)]

Dose: 0.3-0.4 mg/kg/day diphenoxylate PO divided qid; Start: 0.3-0.4 mg/kg/day diphenoxylate PO divided qid, then may decr. maint. dose by up to 25% once sx controlled; Info: use oral solution only; reduce dose based on nutritional, hydration status and when sx controlled; D/C after 10 days if no improvement

[13 yo and older]

Dose: 1-2 tabs PO bid-qid prn; Start: 2 tabs PO qid; Max: 8 tabs/day; Info: reduce dose when sx controlled; D/C after 10 days if no improvement

renal dosing

[see below]

renal impairment: not defined; Info: caution advised in advanced hepatorenal dz

HD/PD: not defined

hepatic dosing

[see below]

hepatic impairment: not defined, caution advised; obstructive jaundice: contraindicated