Select a medication above to begin.
atracurium
generic
Adult Dosing .
Dosage forms: INJ
neuromuscular blockade induction
- [400-500 mcg/kg/dose IV x1]
- Info: decr. dose to 250-350 mcg/kg/dose IV x1 if under isoflurane or enflurane anesthesia, 300-400 mcg/kg/dose IV x1 if following succinylcholine-assisted intubation, severe cardiovascular dz or anaphylactic rxn hx; onset 2-2.5min, 25% recovery 35-45min (intermediate-acting)
neuromuscular blockade maintenance
- [intermittent IV]
- Dose: 80-100 mcg/kg/dose IV q15-25min prn; Start: 20-45min after induction dose; Info: higher doses up to 200 mcg/kg/dose may be given less frequently
- [continuous IV]
- Dose: 5-9 mcg/kg/min IV; Start: 9-10 mcg/kg/min IV after induction dose; Info: rates may vary widely between 2-15 mcg/kg/min; decr. rate 33% if under isoflurane or enflurane anesthesia, 50% if undergoing CABG w/ induced hypothermia
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
neuromuscular blockade induction
- [1-23 mo]
- Dose: 300-400 mcg/kg/dose IV x1; Info: onset 2-2.5min, 25% recovery 35-45min (intermediate-acting)
- [2 yo and older]
- Dose: 400-500 mcg/kg/dose IV x1; Info: decr. dose to 250-350 mcg/kg/dose IV x1 if under isoflurane or enflurane anesthesia, 300-400 mcg/kg/dose IV x1 if following succinylcholine-assisted intubation, severe cardiovascular dz or anaphylactic rxn hx; onset 2-2.5min, 25% recovery 35-45min (intermediate-acting)
neuromuscular blockade maintenance
- [intermittent IV, 1 mo and older]
- Dose: 80-100 mcg/kg/dose IV q15-25min prn; Start: 20-45min after induction dose; Info: may require more frequent dosing than adults
- [continuous IV, 1 mo and older]
- Dose: 5-9 mcg/kg/min IV; Start: 9-10 mcg/kg/min IV after induction dose; Info: rates may vary widely between 2-15 mcg/kg/min; decr. rate 33% if under isoflurane or enflurane anesthesia, 50% if undergoing CABG w/ induced hypothermia
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [not defined]