clofarabine

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments

ALL, relapsed or refractory

[18-21 yo]

Dose: 52 mg/m^2/dose IV x1 on days 1-5 of 14- to 42-day cycle; Info: for pts who have received at least 2 prior tx

renal dosing

[adjust dose amount]

CrCl 30-60: decr. usual dose by 50%; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments

ALL, relapsed or refractory

[1 yo and older]

Dose: 52 mg/m^2/dose IV x1 on days 1-5 of 14- to 42-day cycle; Info: for pts who have received at least 2 prior tx

renal dosing

[adjust dose amount]

CrCl 30-60: decr. usual dose by 50%; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[not defined]