Relistor

Adult Dosing .

Dosage forms:  TAB: 150 mg; INJ (pre-filled syringe): 8 mg per 0.4 mL, 12 mg per 0.6 mL; INJ (vial): 12 mg per 0.6 mL

constipation, opioid-induced

[chronic non-cancer pain pts]

Dose: 450 mg PO qam; Alt: 12 mg SC qd; Info: for pts w/ chronic non-cancer pain, incl. pain related to prior cancer or tx; give tab w/ water >30min before first meal

[palliative care pts, <38 kg]

Dose: 0.15 mg/kg/dose SC qod prn; Max: 1 dose/24h

[palliative care pts, 38-61 kg]

Dose: 8 mg SC qod prn; Max: 1 dose/24h

[palliative care pts, 62-114 kg]

Dose: 12 mg SC qod prn; Max: 1 dose/24h

[palliative care pts, >114 kg]

Dose: 0.15 mg/kg/dose SC qod prn; Max: 1 dose/24h

renal dosing

[PO route]

CrCl <60: 150 mg PO qam

HD/PD: not defined

[SC route]

CrCl <60: decr. usual dose by 50%

HD/PD: not defined

hepatic dosing

[PO route]

Child-Pugh Class B or C: 150 mg PO qam

[SC route]

Child-Pugh Class C: consider decr. usual dose by 50%

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.