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Mirapex ER
pramipexole
Adult Dosing .
Dosage forms: ER TAB: 0.375 mg, 0.75 mg, 1.5 mg, 2.25 mg, 3 mg, 3.75 mg, 4.5 mg
Parkinson dz
- [0.375-4.5 mg PO qd]
- Start: 0.375 mg PO qd x5-7 days, then 0.75 mg PO qd x5-7 days, then may incr. by 0.75 mg/day q5-7 days; Max: 4.5 mg/day; Info: switch from IR to ER overnight at same daily dose; do not cut/crush/chew tab; taper dose by 0.75 mg/day to 0.75 mg PO qd, then taper dose by 0.375 mg/day to D/C
renal dosing
- [adjust dose frequency]
- CrCl 30-50: start 0.375 mg qod x7 days, then 0.375 mg qd x7 days, then may incr. by 0.375 mg/day q7 days, max 2.25 mg/day; CrCl <30: not defined
- HD/PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.