pilocarpine ophthalmic

Adult Dosing .

Dosage forms:  SOL: 1%, 2%, 4%

elevated IOP

[open-angle glaucoma or ocular HTN]

Dose: 1 gtt (1%, 2%, or 4%) in eye(s) up to qid; Info: start w/ 1% in pilocarpine-naive pts

[acute angle-closure glaucoma]

Dose: 1 gtt (1% or 2%) in eye(s) up to 3 doses over 30min; Info: for initial management, short-term tx; if laser iridoplasty, give 1 gtt (4%) in eye(s) x1 before procedure, then 1 gtt (1%) in eye(s) qid until iridotomy; give 1 gtt (4%) in eye(s) x1 before iridotomy

elevated IOP prevention, postop

[1-2 gtt (1%, 2%, or 4%) in eye(s) x1]

Start: 15-60min before laser surgery; Info: space gtt 5min apart

miosis induction

[1-2 gtt (1%, 2%, or 4%) in eye(s) x1]

Start: 15-60min before surgery; Info: space gtt 5min apart

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  SOL: 1%, 2%, 4%

elevated IOP

[open-angle glaucoma or ocular HTN, <2 yo]

Dose: 1 gtt (1%) in eye(s) tid

[open-angle glaucoma or ocular HTN, 2 yo and older]

Dose: 1 gtt (1%, 2%, or 4%) in eye(s) up to qid; Info: start w/ 1% in pilocarpine-naive pts

[acute angle-closure glaucoma, 2 yo and older]

Dose: 1 gtt (1% or 2%) in eye(s) up to 3 doses over 30min; Info: for initial management, short-term tx; if laser iridoplasty, give 1 gtt (4%) in eye(s) x1 before procedure, then 1 gtt (1%) in eye(s) qid until iridotomy; give 1 gtt (4%) in eye(s) x1 before iridotomy

miosis induction

[1 gtt (1% or 2%) in eye(s) x1]

Start: 15-60min before surgery

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]