gamma-glutamylethylamide

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• ADHD [Insufficient Evidence]
• Alzheimer dz [Insufficient Evidence]
• anxiety [Insufficient Evidence]
• attention [Insufficient Evidence]
• cancer [Insufficient Evidence]
• cognitive decline, age-related [Insufficient Evidence]
• cognitive function [Possibly Effective]
• cognitive impairment [Insufficient Evidence]
• depression [Insufficient Evidence]
• diarrhea, chemo-related [Insufficient Evidence]
• erythema [Insufficient Evidence]
• generalized anxiety disorder [Insufficient Evidence]
• HTN [Insufficient Evidence]
• influenza [Insufficient Evidence]
• insomnia [Insufficient Evidence]
• obsessive-compulsive disorder [Insufficient Evidence]
• postop recovery [Insufficient Evidence]
• schizophrenia [Insufficient Evidence]
• stress [Insufficient Evidence]
• Tourette syndrome [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies w/ variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

ADHD, peds pts

[Insufficient Evidence]

Dose: 2.5 mg/kg/dose PO x1; Alt: 200 mg PO bid in pts 8-12 yo

anxiety

[Insufficient Evidence]

Dose: 200 mg PO qd

attention

[Insufficient Evidence]

Dose: 100-400 mg PO x1; Info: used w/ or w/o caffeine

cognitive decline, age-related

[Insufficient Evidence]

Dose: 101 mg PO x1

cognitive function

[Possibly Effective]

Dose: 100 mg PO x1; Alt: 200 mg PO qd

cognitive impairment

[Insufficient Evidence]

Dose: 120 mg PO bid; Info: give after meals

depression

[Insufficient Evidence]

Dose: 250 mg PO qhs; Alt: 200 mg PO qd; Info: used w/ or w/o sertraline

diarrhea, chemo-related

[Insufficient Evidence]

Dose: 280 mg PO qd; Start: 1wk before chemo tx

influenza

[Insufficient Evidence]

Dose: 210 mg PO qd; Info: used w/ green tea catechins

insomnia

[Insufficient Evidence]

Dose: 50 mg PO qhs given 60min before desired bedtime; Alt: 50 mg PO x1 given 10min before desired bedtime; 200 mg PO qhs given 120min before desired bedtime

obsessive-compulsive disorder

[Insufficient Evidence]

Dose: 100 mg PO bid; Info used w/ fluvoxamine

postop recovery

[Insufficient Evidence]

Dose: 280 mg PO qd; Start: 4 days before surgery; Info: used w/ cystine

schizophrenia

[Insufficient Evidence]

Dose: 200 mg PO bid; Alt: 400 mg PO qd; Info: used w/ antipsychotic tx; used w/ or w/o pregnenolone

stress

[Insufficient Evidence]

Dose: 200 mg PO x1; Alt: 200 mg PO bid; 50 mg PO qam

Tourette syndrome, peds pts

[Insufficient Evidence]

Dose: 200 mg PO qd; Info: for pts 4-17 yo