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Medical News for You

FDA

FDA approves gene therapy Genglycos, first treatment targeting cause of glycogen storage disease type Ia

One-time IV gene therapy may reduce the need for around-the-clock cornstarch in patients aged 8 years and older. . .

JAMA Psychiatry/Addict Behav

Cannabis use disorder climbs, as alcohol use disorder flattens

Severity is rising across most age and sex groups, and how a patient uses cannabis may signal who needs a closer look. . .

JAMA Netw Open

Patients read test results first, often without context

About one-third rated their understanding as less than solid, with clinician communication habits linked to higher comprehension. . .

Circ Popul Health Outcomes

Artery injury is already showing up in adults in their 20s

Nearly 80% of young adults had cardiovascular-kidney-metabolic risk factors, and more advanced CKM stages tracked with signs of early carotid artery injury. . .

PLOS Digit Health

AI medical device clearance skips outcomes data

Built around equivalence to devices already on the market, the 510(k) pathway now clears most systems that diagnose, screen, and increasingly guide treatment. . .

Nat Ment Health

New genetic clues point beyond body weight in eating disorders

Largest genetic study to date of anorexia nervosa—and the first large-scale comparison of binge-eating genetics—finds distinct links that BMI alone cannot explain. . .

FDA

FDA greenlights Pasatru, first-in-class antibody for rare bone-forming disease

Pasatru (garetosmab-grts) directly targets a key driver of abnormal bone formation in adults with fibrodysplasia ossificans progressiva. . .

BMJ

Preoperative IV iron cuts transfusion needs in cardiac surgery

In patients with anemia, treatment meant about 7 fewer transfusions for every 100 patients treated. . .

Pharmacotherapy

10h

New evidence strengthens case for prolonged-infusion beta-lactams in critically ill patients

Updated international consensus finds improved survival and clinical cure with prolonged infusion versus standard short infusion in severely ill adults. . .