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Science

Genetic mutation linked to 25x lung cancer risk

The variant carries lung cancer risk exceeding that conferred by smoking, and the effect runs highest in people who have never smoked. . .

Am J Prev Med

Gambling disorder ED visits double in young men

Emergency visits climbed steadily after Ontario scaled online gambling access. . .

Eur Heart J

Cardiometabolic whole grain benefits peak at four to six servings

Improvements in lipids, blood pressure, glucose, and inflammation were individually modest but clustered at that intake level. . .

Anaesthesia

GLP-1s tied to 11x higher risk under surgical anesthesia

Regurgitation of stomach contents occurred at a much higher rate, most often as patients woke from anesthesia. . .

FDA

FDA approves Fayuvi gene therapy, first treatment for Sanfilippo syndrome type A

The single-dose treatment targets the enzyme deficiency underlying a rare inherited disorder that causes progressive loss of cognitive, language, and motor function. . .

Obstet Gynecol

New toolkit helps clinicians navigate perimenopause hormone choices

Guidance highlights when to use hormonal contraception, menopause hormone therapy, or both for symptom management and cycle control. . .

HHS

USPSTF refill draws AMA warning over lack of primary care

The eight appointees restore the panel that grades preventive services to its full 16 members, a slate the physicians' group says departs from the primary care membership behind the task force's credibility. . .

JAMA Netw Open

Primary care panel load tied to clinician burnout

An access-expansion push that filled VA panels past calculated capacity was accompanied by more clinician burnout and intention to leave. . .

Science

Generalist AI helped radiologists catch 10% more on abdominal CT

Previous imaging AI models handled one disease per model; this system covered 146 findings across 18 organs and held up in emergency scans it never trained on. . .