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ApoB may better identify cardiovascular risk than LDL cholesterol, according to a computer simulation study. . .

Large genome-wide study links common genetic variants to modest differences in weight loss and GI side effects with GLP‑1 receptor agonists. . .

A mega-analysis across multiple psychedelic compounds found consistent brain effects that reduced within-network connectivity and increased cross-network communication. . .

A single patient with three severe autoimmune diseases achieved treatment-free remission after CAR-T therapy. . .

A phase 3 study found that SC teprotumumab significantly reduced proptosis at 24 weeks compared with placebo, with efficacy similar to IV treatment. . .

A Vero cell–derived yellow fever vaccine (vYF) achieved ~99% seroconversion with a safety profile comparable to YF-VAX, offering a potential solution to long standing supply constraints. . .

Higher optimism was associated with a lower risk of developing dementia in older adults. . .

In patients with established cardiovascular disease, calcium—especially without vitamin D—was associated with a modest but significant rise in repeat events. . .

Greater adherence to high-quality, plant-based diets was associated with lower dementia risk, with diet quality influencing the strength and direction of the association. . .