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JAMA Netw Open

Surgery may beat GLP-1s on long-term costs

In adults with obesity and diabetes, bariatric metabolic surgery was linked to lower downstream health care costs than GLP-1 therapy. . .

JAMA Netw Open

Primary care CGM starts tied to lower A1c, fewer hospital visits

Among adults with insulin-treated diabetes, continuous glucose monitor use initiated without an endocrinology referral was tied to improvements on par with those seen in specialty settings. . .

JAMA

GLP-1 telehealth sites prescribe fast, skip screening

Secret shoppers got GLP-1 scripts from 45 of 49 online sellers, mostly within a day and some with no clinician contact at all. . .

Ann Intern Med

Can a virtual consult avert a patient transfer?

A systematic review links telemedicine-assisted transfer decisions with fewer interhospital transfers and no signal of increased mortality. . .

FDA

FDA grants first interchangeable rituximab biosimilar

Truxima's new designation may support broader biosimilar adoption across infusion centers and health systems.. . .

Cancer

Cancer screening gaps persist for sexual and gender minorities

National survey data reveal substantially lower breast and cervical cancer screening rates, especially among transgender individuals. . .

Drug pipeline

Novel intranasal therapy shows signal in very severe social anxiety disorder

Post hoc analysis identified a potential benefit in patients with very severe disease after the phase 3 trial missed its primary endpoint.. . .

N Engl J Med

Could a lower-cost MS therapy match ocrelizumab?

Rituximab, an off-label anti-CD20 option, matched ocrelizumab on MRI disease control in a phase 3 trial. . .

Ann Intern Med

10h

Small sleep declines drove weight gain in at-risk adults

Six weeks of sleeping about 80 minutes less per night raised body weight and sedentary time in adults at cardiometabolic risk. . .

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