By vgreene, 21 June, 2021 In seropositive pts w Lyme arthritis needing more definitive info for tx decisions use PCR of synovial fluid or tissue over cx 4
By vgreene, 21 June, 2021 If CSF testing is done perform simultaneous serum sample for determination of CSF serum Ab index don t perform CSF serology alone or perform CSF PCR or cx4
By vgreene, 21 June, 2021 Perform 2 tier testing over PCR or cx of blood CSF or synovial fluid initial ELISA1 2 or IFA 1 then Western immunoblot or FDA approved 2nd EIA3 if 1st test is or equivocal 1 don t r o dx if tests are but there s high clinical suspicion of Lyme dz2
By vgreene, 18 June, 2021 NICE-recommended abx dosing/duration for hemodynamically unstable Lyme carditis:<sup>3</sup>
By vgreene, 18 June, 2021 NICE recommended abx dosing duration for hemodynamically unstable Lyme carditis 3