By vgreene, 11 May, 2020 Observational cohort study w/ propensity score matching; 1,376 consecutive hospitalized pts (60% pts >60y) w/ confirmed mod-severe COVID-19; 811 pts treated w/ HCQ 600 mg bid x2, then 400 mg daily x4 days, 565 pts did not receive HCQ; 45% pts also treated
By vgreene, 8 May, 2020 See <a href=https://clinicaltrials.gov/ct2/results?cond=&term=covid+AND+%28atorvastatin+OR+rosuvastatin+OR+simvastatin+OR+pravastatin+OR+pitavastatin+OR+fluvastatin%29&cntry=&state=&city=&dist=&Search=Search><b><u>all statin trials,</u></b></a> including
By vgreene, 8 May, 2020 Proposed mechanism: reduces inflammatory response by mitigating cytokine activation pathways; attenuates CV component or complications assoc w/ COVID-19; epidemiological data suggest protective effects in influenza pneumonia