By vgreene, 2 April, 2020 Published: Effective Treatment of Severe COVID-19 Patients with Tocilizumab
By vgreene, 2 April, 2020 Treated pts had clinical improvement w/in a few days; all pts had normalized temp on day 1; 15/20 pts had lower O2 intake, 1 needed no O2; CT lesions absorbed in 19; lymphocyte count normalized in 10/19 by day 5; CRP decreased significantly in 16/19 pts;
By vgreene, 2 April, 2020 Retrospective study; 21 severely ill, hospitalized pts (mean age 57y; 4 pts critically ill) w/ confirmed COVID-19 treated w/ TCZ 400 mg x1 after 7 days of routine tx (3 pts received 2nd dose w/in 12h); study pts also received LPV/r, methylprednisolone in
By vgreene, 2 April, 2020 Randomized Trial of Losartan for Patients With COVID-19 Not Requiring Hospitalization, NCT04311177
By vgreene, 2 April, 2020 Comparison of Therapeutics for Hospitalized Patients Infected With SARS-CoV-2 in a Pragmatic aDaptive Randomized Clinical Trial During the COVID-19 Pandemic (COVID MED Trial), NCT04328012
By vgreene, 2 April, 2020 Randomized Controlled Trial of Losartan for Patients With COVID-19 Requiring Hospitalization, NCT04312009