By vgreene, 27 March, 2020 On day 7, viral nucleic acid in throat swab (primary endpoint) was negative in 86.7% of HCQ group vs 93.3% of control group; median time from hospitalization to negative conversion was 4 (1-9) days in HCQ group vs 2 (1-4) days in control group; median tim
By vgreene, 27 March, 2020 Randomized, controlled trial: 30 tx-naïve, hospitalized pts w/ confirmed COVID-19 randomized to HCQ 400 mg daily x5 days or placebo, in addition to conventional tx
By vgreene, 27 March, 2020 Study considerations: non-randomized, open-label study; control group incl pts excluded from tx arm; small sample size; limited long-term safety f/u; high rate of mild-moderate dz; virologic (not clinical) outcomes measured
By vgreene, 27 March, 2020 Nitric Oxide Gas Inhalation for Prevention of COVID-19 in Healthcare Providers, NCT04312243
By vgreene, 27 March, 2020 Subjects will breathe NO at the beginning of each shift and before leaving hospital