By vgreene, 27 March, 2020 Umifenovir (Arbidol): used in Russia & China for tx of influenza; proposed mechanism: inhibits fusion of viral and cellular membranes by intercalating into membrane lipids
By vgreene, 27 March, 2020 Favipravir (AKA favilavir, fapilavir, Avigan): used in Japan for tx of influenza; first approved drug in China for tx of COVID-19; proposed mechanism: terminates viral replication by binding to RNA-dependent RNA polymerase
By vgreene, 27 March, 2020 Proposed mechanism: reduces inflammatory response by inhibiting IL-6 receptors
By vgreene, 27 March, 2020 Proposed mechanism: reduces inflammatory response by inhibiting IL-6 receptors