By vgreene, 27 March, 2020 Proposed mechanism: interferes w/ maturation of viral particles by inhibiting protease enzymes
By vgreene, 27 March, 2020 Proposed mechanism: terminates viral replication by binding to RNA-dependent RNA polymerase; circumvents proofreading activity by exonucleases
By vgreene, 27 March, 2020 Azithromycin: proposed mechanism: no direct antiviral activity; indirect immunomodulatory effects
By vgreene, 27 March, 2020 Proposed mechanism: inhibits viral entry and replication via intracellular alkalinization, interferes w/ maturation of viral particles through impaired glycosylation; indirect immunomodulatory effects
By vgreene, 26 March, 2020 Upcoming: A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia (COVACTA)