By vgreene, 18 February, 2020 Titration Set FPG target choose evidence based titration algorithm eg increase 2 units q3 days to reach FPG target w o hypoglycemia for hypoglycemia determine cause if no clear reason Lower dose by 10 20
By vgreene, 18 February, 2020 Consider insulin as the 1st injectable if: evidence of ongoing catabolism; sx of hyperglycemia present; A1C >10% or blood glucose levels are very high (≥300 mg/dL; or dx of T1DM is a possibility)
By vgreene, 18 February, 2020 If already on GLP 1 RA GLP 1 RA not appropriate or insulin preferred see Add basal insulin below
By vgreene, 18 February, 2020 Consider GLP-1 RA1 in most pts prior to insulin [B]: Initiate appropriate start dose (varies by agent w/in class) and gradually titrate to maintenance (varies by agent)
By vgreene, 18 February, 2020 Efficacy, hypoglycemia risk,<sup>3</sup> and wt concerns to consider when selecting antihyperglycemic tx: