(BMJ)—A healthy 50-yo female smoker presented w/ 3 days of pain and redness in her L breast. Exam: T=100.4°F; L breast: tender, wedge-shaped area of redness w/o mass or fluctuance; no nipple discharge or axillary adenopathy. What is the dx?
Mammary duct ectasia
Inflammatory breast CA
MRSA abscess
Mastitis
Squamous cell carcinoma
You are correct. Nonlactating women may present w/ a painful red breast because of periductal inflammation, or mastitis, which can evolve into a breast abscess. Smoking and nipple piercing are risk factors for mastitis in nonlactating women. Mastitis must be differentiated from inflammatory breast CA, which is rare and may be assoc w/ rapid, global breast swelling, absence of fever/leukocytosis, generalized peau d’orange, and axillary lymphadenopathy. Consider inflammatory breast CA in pts w/ mastitis who don’t respond to warm compresses and oral abx.
By vgreene, 11 August, 2016
By vgreene, 11 August, 2016
By vgreene, 11 August, 2016
By vgreene, 11 August, 2016
By vgreene, 11 August, 2016
By vgreene, 11 August, 2016
(BMJ)—A 62-yo woman presented w/ a headache x10 days, a painful L-sided rash x8 days, and a red, painful, photophobic L eye x1 day. Exam: red skin from L upper lid to forehead, w/ scabbed lesions. L eye: VA 20/30, diffuse conjunctival injection, no fluorescein uptake, 1+ cells/flare, IOP WNL. What is the dx?
Coxsackievirus
Herpes simplex virus
Herpes zoster ophthalmicus
Impetigo
Lymphangioma circumscriptum
You are correct. The pt was diagnosed clinically w/ herpes zoster ophthalmicus (HZO) w/ assoc anterior uveitis, which occurs in 40% to 50% of all cases of HZO. HZO can be distinguished from HSV by the dermatomal distribution of rash. Tx is w/ oral antivirals, pain control, and referral to ophthalmology w/in 24h if there is eye involvement. This pt’s eye sx resolved, and VA returned to 20/20, after 1wk of topical dexamethasone and oral acyclovir. The lesions resolved after 6wk, though she had residual forehead numbness.

BMJ 2016;353:i3221