By vgreene, 4 August, 2016 Autonomic sx. Orthostasis: Lifestyle modifications + limit drugs that lower BP; as dysautonomia worsens, midodrine or fludrocortisone may be necessary. If erectile dysfunction: Phosphodiesterase inhibitors
By vgreene, 4 August, 2016 REM-sleep behavior disorder. Melatonin 3 mg taken 30-60 min qhs to start, increased as needed to max of 12 mg qhs.6 If not effective/tolerated, then clonazepam at 0.5-2 mg qhs7
By vgreene, 4 August, 2016 Neuropsychiatric sx. If delusions/hallucinations are mild/nonbothersome: Behavior interventions (eg, frequent redirection) may suffice. If insufficient, then 1st-line drugs: Cholinesterase inhibitors2,3 (donepezil, rivastigmine, galantamine). 2nd-line dru
By vgreene, 4 August, 2016 Cognitive sx. Cholinesterase inhibitors2 (donepezil, rivastigmine, galantamine) are often helpful. Adding memantine may also be helpful
By vgreene, 4 August, 2016 R/O treatable causes (✓TSH, B12, MRI,3 etc). If Dementia w/ Lewy bodies suspected, refer to neurologist for further eval