Ann Intern Med

Adults with metabolic syndrome could benefit from time-restricted eating

October 4, 2024

An 8- to 10-hour time-restricted eating (TRE) regimen, when combined with standard-of-care (SOC) treatments, can modestly improve glycemic regulation in adults with metabolic syndrome. The findings from this randomized controlled trial suggest that TRE is a safe and practical lifestyle intervention that can enhance cardiometabolic health alongside standard treatments.

Participants (N=108) were randomly assigned to either SOC nutritional counseling or a combination of SOC and a personalized TRE intervention for 3 months. Those in the TRE group reduced their eating window by ≥4 hrs, monitored via the myCircadianClock app. Primary outcomes included HbA1c, fasting glucose, fasting insulin, and insulin resistance.

The TRE group showed a modest improvement in HbA1c levels by -0.10% compared with the SOC group (95% CI, -0.19% to -0.003%). The study reported no major adverse events.

Source:

Manoogian ENC, et al. (2024, October 1). Ann Intern Med. Time-Restricted Eating in Adults With Metabolic Syndrome : A Randomized Controlled Trial. https://pubmed.ncbi.nlm.nih.gov/39348690/