NIH

Zebra of the Week: Tenosynovial giant cell tumor

February 24, 2025

Tenosynovial giant cell tumor is a condition characterized by abnormal growth of the synovium, resulting in a noncancerous mass or tumor. There are two types: the local or nodular form and the diffuse form. Symptoms may include pain, limited movement, and joint locking. In some cases, the normal joint structure can be destroyed. While the knee is most commonly affected, this condition can also occur in other joints, such as the hip, shoulder, elbow, ankle, wrist, and, though rarely, the jaw. The cause of tenosynovial giant cell tumor remains unknown.

Source:

NIH GARD. (Accessed 2025, February 20). Tenosynovial giant cell tumor, diffuse type. https://rarediseases.info.nih.gov/diseases/7396/tenosynovial-giant-cell-tumor-diffuse-type