Highlights & Basics
- Atypical pneumonia (non-COVID-19) is a community-acquired infection often seen in young adults or children living in close proximity.
- Diagnosis is mostly clinical. Molecular-based diagnosis of nasopharyngeal swabs, throat swabs or sputum can be performed. Serology can be used to confirm the diagnosis.
- Treatment is often outpatient based with a macrolide antibiotic or doxycycline.
- Extrapulmonary manifestations may occur, especially in Mycoplasma pneumoniae infections.
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History & Exam
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Definition
Epidemiology
Etiology
Pathophysiology
Citations
Metlay JP, Waterer GW, Long AC, et al. Diagnosis and treatment of adults with community-acquired pneumonia: an official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-67.[Abstract][Full Text]
Lim WS, Baudouin SV, George RC, et al; Pneumonia Guidelines Committee of the BTS Standards of Care Committee. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax. 2009 Oct;64 Suppl 3:iii1-55.[Abstract][Full Text]
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47. Naucler P, Strålin K. Routine atypical antibiotic coverage is not necessary in hospitalised patients with non-severe community-acquired pneumonia. Int J Antimicrob Agents. 2016 Aug;48(2):224-5.[Abstract]
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49. File TM Jr, Eckburg PB, Talbot GH, et al. Macrolide therapy for community-acquired pneumonia due to atypical pathogens: outcome assessment at an early time point. Int J Antimicrob Agents. 2017 Aug;50(2):247-51.[Abstract]
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90. Stets R, Popescu M, Gonong JR, et al. Omadacycline for community-acquired bacterial pneumonia. N Engl J Med. 2019 Feb 7;380(6):517-27.[Abstract][Full Text]
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