Highlights & Basics
- Cauda equina syndrome (CES) is caused by compression of the lumbosacral nerve roots of the cauda equina.
- CES is a neurosurgical emergency, and delays in diagnosis and treatment may lead to permanent disability.
- Features of CES include: low back pain; bilateral or unilateral sciatica; progressive neurologic deficits; difficulty starting or stopping urination or impaired sensation of urinary flow; urgency; urinary retention with overflow urinary incontinence; loss of sensation of rectal fullness; fecal incontinence; laxity of the anal sphincter; saddle anesthesia or paraesthesia; and sexual dysfunction.
- Not all patients show all of the above features, but bladder dysfunction is an essential component of CES.
- Magnetic resonance imaging is carried out as soon as possible in patients with suspected CES.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Citations
Todd NV, Dickson RA. Standards of care in cauda equina syndrome. Br J Neurosurg. 2016 Oct;30(5):518-22.[Abstract]
The Royal College of Emergency Medicine. Cauda equina syndrome position statement. Feb 2020 [internet publication].[Full Text]
Finucane LM, Downie A, Mercer C, et al. International framework for red flags for potential serious spinal pathologies. J Orthop Sports Phys Ther. 2020 Jul;50(7):350-72.[Abstract][Full Text]
Expert Panel on Neurological Imaging., Hutchins TA, Peckham M, et al. ACR appropriateness criteria® low back pain: 2021 update. J Am Coll Radiol. 2021 Nov;18(11s):S361-79.[Abstract][Full Text]
Germon T, Ahuja S, Casey ATH, et al. British Association of Spine Surgeons standards of care for cauda equina syndrome. Spine J. 2015 Mar 2;15(3 suppl):S2-4.[Abstract]
Chau AM, Xu LL, Pelzer NR, et al. Timing of surgical intervention in cauda equina syndrome: a systematic critical review. World Neurosurg. 2014 Mar-Apr;81(3-4):640-50.[Abstract][Full Text]
Epstein NE. Review/perspective: operations for cauda equina syndromes - "The sooner the better". 2022 Mar 25;13:100.[Abstract][Full Text]
1. Todd NV, Dickson RA. Standards of care in cauda equina syndrome. Br J Neurosurg. 2016 Oct;30(5):518-22.[Abstract]
2. Hur JW, Park DH, Lee JB et al. Guidelines for cauda equina syndrome management. J Neurointensive Care. 2019;2(1):14-16.[Full Text]
3. Shivji F, Tsegaye M. Cauda equina syndrome: the importance of complete multidisciplinary team management. BMJ Case Rep. 2013 Mar 15;2013:bcr2012007806.[Abstract][Full Text]
4. Spector LR, Madigan L, Rhyne A, et al. Cauda equina syndrome. J Am Acad Orthop Surg. 2008 Aug;16(8):471-9.[Abstract]
5. Comer C, Finucane L, Mercer C, et al. SHADES of grey - The challenge of 'grumbling' cauda equina symptoms in older adults with lumbar spinal stenosis. Musculoskelet Sci Pract. 2020 Feb;45:102049.[Abstract][Full Text]
6. The Royal College of Emergency Medicine. Cauda equina syndrome position statement. Feb 2020 [internet publication].[Full Text]
7. Barraclough K. Cauda equina syndrome. BMJ. 2021 Jan 12;372:n32.[Abstract]
8. Finucane LM, Downie A, Mercer C, et al. International framework for red flags for potential serious spinal pathologies. J Orthop Sports Phys Ther. 2020 Jul;50(7):350-72.[Abstract][Full Text]
9. Hoeritzauer I, Wood M, Copley PC, et al. What is the incidence of cauda equina syndrome? A systematic review. J Neurosurg Spine. 2020 Feb 14:1-10.[Abstract][Full Text]
10. Kirshblum SC, Burns SP, Biering-Sorensen F, et al. International standards for neurological classification of spinal cord injury (revised 2011). J Spinal Cord Med. 2011 Nov;34(6):535-46.[Abstract][Full Text]
11. Tetsuka S, Suzuki T, Ogawa T, et al. Spinal epidural abscess: a review highlighting early diagnosis and management. JMA J. 2020 Jan 15;3(1):29-40.[Abstract][Full Text]
12. United Kingdom Spine Societies Board. Early recognition of cauda equina syndrome a framework for assessment and referral for primary care/MSK interface services. Jul 2022 [internet publication].[Full Text]
13. Kuris EO, McDonald CL, Palumbo MA, et al. Evaluation and management of cauda equina syndrome. Am J Med. 2021 Dec;134(12):1483-9.[Abstract]
14. American College of Radiology. ACR appropriateness criteria low back pain. 2021 [internet publication].[Full Text]
15. Expert Panel on Neurological Imaging., Hutchins TA, Peckham M, et al. ACR appropriateness criteria® low back pain: 2021 update. J Am Coll Radiol. 2021 Nov;18(11s):S361-79.[Abstract][Full Text]
16. Todd NV. Guidelines for cauda equina syndrome. Red flags and white flags. Systematic review and implications for triage. Br J Neurosurg. 2017 Jun;31(3):336-9.[Abstract]
17. Verhagen AP, Downie A, Popal N, et al. Red flags presented in current low back pain guidelines: a review. Eur Spine J. 2016 Sep;25(9):2788-802.[Abstract][Full Text]
18. Galliker G, Scherer DE, Trippolini MA, et al. Low back pain in the emergency department: prevalence of serious spinal pathologies and diagnostic accuracy of red flags. Am J Med. 2020 Jan;133(1):60-72.[Abstract]
19. Cook CE, George SZ, Reiman MP. Red flag screening for low back pain: nothing to see here, move along: a narrative review. Br J Sports Med. 2018 Apr;52(8):493-6.[Abstract][Full Text]
20. Greenhalgh S, Truman C, Webster V, et al. Development of a toolkit for early identification of cauda equina syndrome. Prim Health Care Res Dev. 2016 Nov;17(6):559-67.[Abstract][Full Text]
21. Haig AJ, Tong HC, Yamakawa KS, et al. Predictors of pain and function in persons with spinal stenosis, low back pain, and no back pain. Spine (Phila Pa 1976). 2006 Dec 1;31(25):2950-7.[Abstract]
22. Haig AJ, Tong HC, Yamakawa KS, et al. Spinal stenosis, back pain, or no symptoms at all? A masked study comparing radiologic and electrodiagnostic diagnoses to the clinical impression. Arch Phys Med Rehabil. 2006 Jul;87(7):897-903.[Abstract]
23. British Association of Spine Surgeons; The Society of British Neurological Surgeons. Standards of care for investigation and management of cauda equina syndrome. Dec 2018 [internet publication].[Full Text]
24. Germon T, Ahuja S, Casey ATH, et al. British Association of Spine Surgeons standards of care for cauda equina syndrome. Spine J. 2015 Mar 2;15(3 suppl):S2-4.[Abstract]
25. Kirshblum S, Eren F. Anal reflex versus bulbocavernosus reflex in evaluation of patients with spinal cord injury. Spinal Cord Ser Cases. 2020;6:2.[Abstract][Full Text]
26. Lavy C, James A, Wilson-MacDonald J, et al. Cauda equina syndrome. BMJ. 2009 Mar 31;338:b936.[Abstract]
27. Consortium for Spinal Cord Medicine. Early acute management in adults with spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med. 2008;31(4):403-79.[Abstract][Full Text]
28. Gooding BW, Higgins MA, Calthorpe DA. Does rectal examination have any value in the clinical diagnosis of cauda equina syndrome? Br J Neurosurg. 2013 Apr;27(2):156-9.[Abstract]
29. Villanueva Herrero JA, Abdussalam A, Kasi A. Rectal Exam. In: StatPearls. StatPearls Publishing; 2022.[Abstract][Full Text]
30. Dionne N, Adefolarin A, Kunzelman D, et al. What is the diagnostic accuracy of red flags related to cauda equina syndrome (CES), when compared to Magnetic Resonance Imaging (MRI)? A systematic review. Musculoskelet Sci Pract. 2019 Jul;42:125-33.[Abstract]
31. Peacock JG, Timpone VM. Doing more with less: diagnostic accuracy of CT in suspected cauda equina syndrome. AJNR Am J Neuroradiol. 2017 Feb;38(2):391-7.[Abstract]
32. Ginsberg DA, Boone TB, Cameron AP, et al. The AUA/SUFU guideline on adult neurogenic lower urinary tract dysfunction: diagnosis and evaluation. J Urol. 2021 Nov;206(5):1097-105.[Abstract][Full Text]
33. Alshahwani AA, Boktor J, Elbahi A, et al. A systematic review of the value of a bladder scan in cauda equina syndrome diagnosis. Cureus. 2021 Apr 12;13(4):e14441.[Abstract][Full Text]
34. Venkatesan M, Nasto L, Tsegaye M, et al. Bladder scans and postvoid residual volume measurement improve diagnostic accuracy of cauda equina syndrome. Spine (Phila Pa 1976). 2019 Sep;44(18):1303-8.[Abstract]
35. Todd N, Dangas K, Lavy C. Post-void bladder ultrasound in suspected cauda equina syndrome-data from medicolegal cases and relevance to magnetic resonance imaging scanning. Int Orthop. 2022 Jun;46(6):1375-80.[Abstract][Full Text]
36. Pronin S, Hoeritzauer I, Statham PF, et al. Are we neglecting sexual function assessment in suspected cauda equina syndrome? Surgeon. 2020 Feb;18(1):8-11.[Abstract][Full Text]
37. Brouwers E, van de Meent H, Curt A, et al. Definitions of traumatic conus medullaris and cauda equina syndrome: a systematic literature review. Spinal Cord. 2017 Oct;55(10):886-90.[Abstract][Full Text]
38. American College of Surgeons. Best practice guidelines: spine injury. Mar 2022 [internet publication].[Full Text]
39. Society of British Neurological Surgeons. Standards of care for investigation and management of cauda equina syndrome. Dec 2018 [internet publication].[Full Text]
40. Quaile A. Cauda equina syndrome-the questions. Int Orthop. 2019 Apr;43(4):957-61.[Abstract]
41. Chau AM, Xu LL, Pelzer NR, et al. Timing of surgical intervention in cauda equina syndrome: a systematic critical review. World Neurosurg. 2014 Mar-Apr;81(3-4):640-50.[Abstract][Full Text]
42. Epstein NE. Review/perspective: operations for cauda equina syndromes - "The sooner the better". 2022 Mar 25;13:100.[Abstract][Full Text]
43. Hogan WB, Kuris EO, Durand WM, et al. Timing of surgical decompression for cauda equina syndrome. World Neurosurg. 2019 Dec;132:e732-8.[Abstract]
44. Shapiro S. Medical realities of cauda equina syndrome secondary to lumbar disc herniation. Spine (Phila Pa 1976). 2000 Feb 1;25(3):348-51.[Abstract]
45. DeLong WB, Polissar N, Neradilek B. Timing of surgery in cauda equina syndrome with urinary retention: meta-analysis of observational studies. J Neurosurg Spine. 2008 Apr;8(4):305-20.[Abstract]
46. Srikandarajah N, Boissaud-Cooke MA, Clark S, et al. Does early surgical decompression in cauda equina syndrome improve bladder outcome? Spine (Phila Pa 1976). 2015 Apr 15;40(8):580-3.[Abstract]
47. Balzer JR, Rose RD, Welch WC, et al. Simultaneous somatosensory evoked potential and electromyographic recordings during lumbosacral decompression and instrumentation. Neurosurgery. 1998 Jun;42(6):1318-24.[Abstract]
48. Hazelwood JE, Hoeritzauer I, Pronin S, et al. An assessment of patient-reported long-term outcomes following surgery for cauda equina syndrome. Acta Neurochir (Wien). 2019 Sep;161(9):1887-94.[Abstract][Full Text]
49. Gould MK, Garcia DA, Wren SM, et al. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012 Feb;141(2 suppl):e227S-77.[Abstract][Full Text]
50. Kahn SR, Lim W, Dunn AS, et al. Prevention of VTE in nonsurgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012 Feb;141(2 suppl):e195-226.[Abstract][Full Text]
51. Toews I, George AT, Peter JV, et al. Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units. Cochrane Database Syst Rev. 2018 Jun 4;(6):CD008687.[Abstract][Full Text]
52. Ginsberg DA, Boone TB, Cameron AP, et al. The AUA/SUFU guideline on adult neurogenic lower urinary tract dysfunction: treatment and follow-up. J Urol. 2021 Nov;206(5):1106-13.[Abstract][Full Text]
53. Taweel WA, Seyam R. Neurogenic bladder in spinal cord injury patients. Res Rep Urol. 2015;7:85-99.[Abstract][Full Text]
54. Emmanuel A. Neurogenic bowel dysfunction. F1000Res. 2019 Oct 28;8.[Abstract][Full Text]
55. Chen C, Fan P, Huang L, et al. Percutaneous endoscopic lumbar discectomy as an emergent surgery for cauda equina syndrome caused by lumbar disc herniation. Pain Physician. 2020 Jun;23(3):E259-64.[Abstract][Full Text]
56. Yankang L, Leiming Z, Lewandrowski KU, et al. Full endoscopic lumbar discectomy versus laminectomy for cauda equina syndrome. Int J Spine Surg. 2021 Feb;15(1):105-12.[Abstract][Full Text]
57. Korse NS, Veldman AB, Peul WC, et al. The long term outcome of micturition, defecation and sexual function after spinal surgery for cauda equina syndrome. PLoS One. 2017;12(4):e0175987.[Abstract][Full Text]
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