Highlights & Basics
- Febrile seizures are usually self-limiting; increased risk of developing epilepsy is low except in a small number of cases.
- Most febrile seizures resolve spontaneously and quickly, and do not require acute or long-term anticonvulsant treatment.
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Age of occurrence of febrile seizures in 100 consecutive children treated in a university-affiliated tertiary care hospital: maximum frequency between ages 12 and 18 months, with a rapid decline after 24 months of age
Seasonal occurrence of febrile seizures in 100 consecutive children treated in a university-affiliated tertiary care hospital: maximum frequency in spring and winter; lowest frequency in summer months
Citations
American Academy of Pediatrics: Subcommittee on Febrile Seizures. Clinical practice guideline: neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics. 2011 Feb;127(2):389-94.[Abstract][Full Text]
American Academy of Pediatrics. Febrile seizures: clinical practice guideline for the long-term management of the child with simple febrile seizures. Pediatrics. 2008 Jun;121(6):1281-6.[Abstract][Full Text]
Millichap JG, Millichap JJ. Role of viral infections in the etiology of febrile seizures. Pediatr Neurol. 2006 Sep;35(3):165-72.[Abstract]
Fetveit A. Assessment of febrile seizures in children. Eur J Pediatr. 2008 Jan;167(1):17-27.[Abstract]
Graves RC, Oehler K, Tingle LE. Febrile seizures: risks, evaluation, and prognosis. Am Fam Physician. 2012 Jan 15;85(2):149-53.[Abstract][Full Text]
Capovilla G, Mastrangelo M, Romeo A, et al. Recommendations for the management of "febrile seizures": Ad Hoc Task Force of LICE Guidelines Commission. Epilepsia. 2009 Jan; 50(1 suppl):S2-6.[Abstract][Full Text]
Natsume J, Hamano SI, Iyoda K, et al. New guidelines for management of febrile seizures in Japan. Brain Dev. 2017 Jan;39(1):2-9.[Abstract]
Nordli DR Jr. Idiopathic generalized epilepsies recognized by the International League Against Epilepsy. Epilepsia. 2005 Nov 18;46(9 suppl):48-56.[Abstract][Full Text]
Wilmshurst JM, Gaillard WD, Vinayan KP, et al. Summary of recommendations for the management of infantile seizures: task force report for the ILAE Commission of Pediatrics. Epilepsia. 2015 Aug;56(8):1185-97.[Abstract][Full Text]
Dunlop S, Taitz J. Retrospective review of the management of simple febrile convulsions at a tertiary paediatric institution. J Paediatr Child Health. 2005 Dec;41(12):647-51.[Abstract]
Kimia AA, Bachur RG, Torres A, et al. Febrile seizures: emergency medicine perspective. Curr Opin Pediatr. 2015 Jun;27(3):292-7.[Abstract]
Rosenbloom E, Finkelstein Y, Adams-Webber T, et al. Do antipyretics prevent the recurrence of febrile seizures in children? A systematic review of randomized controlled trials and meta-analysis. Eur J Paediatr Neurol. 2013 Nov;17(6):585-8.[Abstract]
Offringa M, Newton R, Nevitt SJ, et al. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2021 Jun 16;(6):CD003031.[Abstract][Full Text]
Baumann RJ, Duffner PK; American Academy of Pediatrics. Treatment of children with simple febrile seizures: the AAP practice parameter. Pediatr Neurol. 2000 Jul;23(1):11-7.[Abstract]
Whelan H, Harmelink M, Chou E, et al. Complex febrile seizures: a systematic review. Dis Mon. 2017 Jan;63(1):5-23.[Abstract][Full Text]
Shinnar S, Glauser TA. Febrile seizures. J Child Neurol. 2002 Jan;17(1 suppl):S44-52.[Abstract]
Camfield P, Camfield C. Febrile seizures and genetic epilepsy with febrile seizures plus (GEFS+). Epileptic Disord. 2015 Jun;17(2):124-33.[Abstract]
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2. American Academy of Pediatrics. Febrile seizures: clinical practice guideline for the long-term management of the child with simple febrile seizures. Pediatrics. 2008 Jun;121(6):1281-6.[Abstract][Full Text]
3. Fisher RS, Cross JH, French JA, et al. Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):522-30.[Abstract][Full Text]
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9. Shinnar S, Hesdorffer DC, Nordli DR Jr, et al; FEBSTAT Study Team. Phenomenology of prolonged febrile seizures: results of the FEBSTAT study. Neurology. 2008 Jul 15;71(3):170-6.[Abstract]
10. Chiu SS, Tse CY, Lau YL, et al. Influenza A infection is an important cause of febrile seizures. Pediatrics. 2001 Oct;108(4):E63.[Abstract][Full Text]
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79. Dunlop S, Taitz J. Retrospective review of the management of simple febrile convulsions at a tertiary paediatric institution. J Paediatr Child Health. 2005 Dec;41(12):647-51.[Abstract]
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