Kerendia

Adult Dosing .

Dosage forms:  TAB: 10 mg, 20 mg

kidney dz progression and cardiovascular-associated risk reduction - DM type 2 pts w/ CKD

[20 mg PO qd]

Info: use for risk reduction of sustained eGFR decline, ESRD, cardiovascular death, non-fatal MI, and heart failure hospitalization; see pkg insert for dose adjustments based on potassium levels

renal dosing

[see below]

eGFR 25-59: start 10 mg qd, may incr. to 20 mg qd after 4wk based on potassium level and eGFR; eGFR <25: avoid tx initiation; Info: see pkg insert for dose adjustments based on potassium levels and eGFR

HD/PD: not defined

hepatic dosing

[see below]

Child-Pugh Class C: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.