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Ibsrela
tenapanor
Black Box Warnings .
Pediatric Risk
contraindicated in pts <6 yo; deaths occurred due to dehydration in nonclinical studies in juvenile rats after oral tenapanor admin; avoid use in pts 6 yo to less than 12 yo; safety and efficacy not established in pts <18 yo
Adult Dosing .
Dosage forms: TAB: 50 mg
IBS, constipation-predominant
- [50 mg PO bid]
- Info: give immediately before meals
renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
hepatic dosing
- [no adjustment]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.