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Xelstrym
dextroamphetamine transdermal
Black Box Warnings .
Abuse, Misuse, and Addiction
CNS stimulants have high potential for abuse and misuse, can lead to substance use disorder, incl. addiction; misuse and abuse can result in overdose and death, risk incr. w/ higher doses or unapproved admin. methods; assess risk for abuse, misuse, and addiction before prescribing and throughout tx; educate pts and families about risks and proper drug storage and disposal; monitor frequently for s/sx of abuse, misuse, and addiction during tx
Adult Dosing .
Dosage forms: PATCH: 4.5 mg per 9h, 9 mg per 9h, 13.5 mg per 9h, 18 mg per 9h
Special Note
- [formulation clarification]
- Info: not interchangeable w/ other amphetamine products; do not substitute on a mg to mg basis; retitrate if switching between products
ADHD
- [apply 1 patch qd x9h, off x15h]
- Start: apply 9 mg patch qd x9h, off x15h; Max: 18 mg/9h patch qd; Info: apply 2h before desired effect; do not cut patch
renal dosing
- [adjust dose amount]
- CrCl 15-30: max 13.5 mg/9h qd; CrCl <15: max 9 mg/9h qd
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: PATCH: 4.5 mg per 9h, 9 mg per 9h, 13.5 mg per 9h, 18 mg per 9h
Special Note
- [formulation clarification]
- Info: not interchangeable w/ other amphetamine products; do not substitute on a mg to mg basis; retitrate if switching between products
ADHD
- [6-17 yo]
- Dose: apply 1 patch qd x9h, off 15h; Start: apply 4.5 mg patch qd x9h, off x15h, then may incr. to next size patch qwk; Max: 18 mg/9h patch qd; Info: apply 2h before desired effect; do not cut patch
renal dosing
- [adjust dose amount]
- CrCl 15-30: max 13.5 mg/9h qd; CrCl <15: max 9 mg/9h qd
- HD/PD: not defined
hepatic dosing
- [not defined]