Amvuttra

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 25 mg per 0.5 mL

transthyretin amyloid polyneuropathy

[25 mg SC q3mo]

Info: for pts w/ hereditary dz; vitamin A supplementation recommended

transthyretin amyloid cardiomyopathy

[25 mg SC q3mo]

Info: for pts w/ hereditary or wild-type dz to reduce cardiovascular death and cardiovascular-associated hospitalization; vitamin A supplementation recommended

renal dosing

[see below]

eGFR >30: no adjustment; eGFR <30 or ESRD: not defined

HD/PD: not defined

hepatic dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.