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Constulose
lactulose
Adult Dosing .
Dosage forms: SOL: 10 g per 15 mL
constipation
- [15-30 mL (10-20 g) PO qd]
- Info: may incr. dose to 60 mL (40 g) PO qd; response may require 24-48h
hepatic encephalopathy (off-label)
- [30-45 mL (20-30 g) PO tid-qid]
- Info: adjust dose to produce 2-3 soft stools/day; for acute episodes give 30-45 mL (20-30 g) PO q1-2h until 2-3 soft stools/day
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: SOL: 10 g per 15 mL
constipation (off-label)
- [1-3 mL/kg/day (0.7-2 g/kg/day) PO divided qd-bid]
- Max: 60 mL/day (40 g/day); Info: response may require 24-48h
hepatic encephalopathy (off-label)
- [infants]
- Dose: 2.5-10 mL/day (1.7-6.7 g/day) PO divided tid-qid; Info: adjust dose to produce 2-3 soft stools/day
- [children/adolescents]
- Dose: 40-90 mL/day (26.7-60 g/day) PO divided tid-qid; Info: adjust dose to produce 2-3 soft stools/day
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]