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Lamzede (velmanase alfa-tycv)
velmanase alfa
Black Box Warnings .
Severe Hypersensitivity Rxn
severe rxns incl. anaphylaxis have occurred; appropriate medical support incl. cardiopulmonary resuscitation equipment should be readily avail. during admin; D/C immediately and start appropriate tx if severe rxn occurs; may consider desensitization procedure in pts w/ severe rxn
Adult Dosing .
Dosage forms: INJ
Special Note
- [formulation clarification]
- Info: nonproprietary name = velmanase alfa-tycv
alpha-mannosidosis
- [1 mg/kg/dose IV qwk]
- Info: for pts w/ non-CNS manifestations; consider premed w/ antihistamine, antipyretic, and/or corticosteroid; see pkg insert for dose adjustments based on hypersensitivity and infusion rxns
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: INJ
Special Note
- [formulation clarification]
- Info: nonproprietary name = velmanase alfa-tycv
alpha-mannosidosis
- [1 mg/kg/dose IV qwk]
- Info: for pts w/ non-CNS manifestations; consider premed w/ antihistamine, antipyretic, and/or corticosteroid; see pkg insert for dose adjustments based on hypersensitivity and infusion rxns
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]