Bimzelx (bimekizumab-bkzx)

Adult Dosing .

Dosage forms:  INJ (auto-injector): 160 mg, 320 mg; INJ (pre-filled syringe): 160 mg per mL, 320 mg per 2 mL

Special Note

[formulation clarification]

Info: nonproprietary name = bimekizumab-bkzx

psoriasis, moderate-severe plaque

[320 mg SC q8wk]

Start: 320 mg SC x1 at wk 0, 4, 8, 12, 16, then 320 mg SC q8wk; Info: may consider 320 mg SC q4wk after wk 16 if wt >120 kg

psoriatic arthritis

[160 mg SC q4wk]

Info: use plaque psoriasis dosing for pts w/ coexisting dz

axial spondyloarthritis, non-radiographic

[160 mg SC q4wk]

ankylosing spondylitis

[160 mg SC q4wk]

hidradenitis suppurativa, moderate-severe

[320 mg SC q4wk]

Start: 320 mg SC x1 at wk 0, 2, 4, 6, 8, 10, 12, 14, 16, then 320 mg SC q4wk

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[see below]

acute hepatic dz/cirrhosis: avoid use

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.