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Zurzuvae
zuranolone
Black Box Warnings .
Impaired Ability to Drive or Engage in Other Potentially Hazardous Activities
causes driving impairment due to CNS depressant effects; advise pts not to drive or engage in other potentially hazardous activities for at least 12h after each dose; inform pts they may not be able to assess driving competence or degree of impairment
Adult Dosing .
Dosage forms: CAP: 20 mg, 25 mg, 30 mg
postpartum depression
- [50 mg PO qpm x14 days]
- Info: give w/ fat-containing food; may decr. dose to 40 mg PO qpm if CNS depression occurs
renal dosing
- [adjust dose amount]
- eGFR 15-59: 30 mg qpm x14 days; eGFR <15: not defined
- HD/PD: not defined
hepatic dosing
- [adjust dose amount]
- Child-Pugh Class C: 30 mg qpm x14 days
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.