Beyfortus (nirsevimab-alip)

Adult Dosing .

Adult dosing is currently unavailable or not applicable for this drug.

Peds Dosing .

Dosage forms:  INJ

Special Note

[formulation clarification]

Info: nonproprietary name = nirsevimab-alip

RSV dz prevention

[<34 wk gestation, <8 mo, <5 kg]

Dose: 50 mg IM x1 dose; Start: before start of RSV season; Info: give <1 wk after birth if born during or entering RSV season; consider additional dose if pt undergoing cardiac surgery w/ cardiopulmonary bypass, see pkg insert; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[<34 wk gestation, <8 mo, >5 kg]

Dose: 100 mg IM x1 dose; Start: before start of RSV season; Info: give <1 wk after birth if born during or entering RSV season; consider additional dose if pt undergoing cardiac surgery w/ cardiopulmonary bypass, see pkg insert; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[>34 wk gestation, <8 mo, <5 kg]

Dose: 50 mg IM x1 dose; Start: before start of RSV season; Info: for infants born to unvaccinated mothers, born to mothers w/ unknown vaccine status, or born <14 days after maternal vaccination; give <1 wk after birth if born during or entering RSV season; consider additional dose if pt undergoing cardiac surgery w/ cardiopulmonary bypass, see pkg insert; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[>34 wk gestation, <8 mo, >5 kg]

Dose: 100 mg IM x1 dose; Start: before start of RSV season; Info: for infants born to unvaccinated mothers, born to mothers w/ unknown vaccine status, or born <14 days after maternal vaccination; give <1 wk after birth if born during or entering RSV season; consider additional dose if pt undergoing cardiac surgery w/ cardiopulmonary bypass, see pkg insert; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

[8-19 mo]

Dose: 200 mg IM x1 dose; Start: before start of 2nd RSV season; Info: for pts at incr. risk for severe RSV dz, American Indian pts, and Alaska Native pts; consider additional dose if pt undergoing cardiac surgery w/ cardiopulmonary bypass, see pkg insert; search 'immunization' for epocrates Child/Adolescent Immunization decision tool incl. links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]