Lantidra (donislecel-jujn)

Adult Dosing .

Dosage forms:  INJ

Restricted Distribution in US

[1-800-500-1617 or www.lantidra.com]

Special Note

[formulation clarification]

Info: nonproprietary name = donislecel-jujn

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, prophylactic immunosuppressants and antimicrobials, and dosing

diabetes mellitus, type 1

[5000 EIN/kg/dose via hepatic portal vein x1]

Max: 1 x10^6 EIN/dose, 10 mL packed islet tissue/dose; Info: for pts w/ uncontrolled dz due to recurrent severe hypoglycemia; may repeat dose w/ 4500 EIN/kg/dose x1 if insulin independence not achieved w/in 1y post-infusion or w/in 1y after losing insulin independence after prior infusion; may give 3rd dose w/ 4500 EIN/kg/dose x1 if insulin independence not achieved w/in 1y post-2nd infusion or w/in 1y after losing insulin independence after 2nd infusion; EIN = equivalent islet number

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.