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Voquezna
vonoprazan
Adult Dosing .
Dosage forms: TAB: 10 mg, 20 mg
erosive esophagitis
- [initial tx]
- Dose: 20 mg PO qd x8wk; Info: do not cut/crush/chew tab
- [maintenance tx]
- Dose: 10 mg PO qd for up to 6mo; Info: do not cut/crush/chew tab
GERD, non-erosive symptomatic
- [10 mg PO qd x4wk]
- Info: do not cut/crush/chew tab
H. pylori infection
- [triple tx]
- Dose: 20 mg PO bid x14 days; Info: give w/ amoxicillin 1 g PO bid and clarithromycin 500 mg PO bid; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool
- [dual tx]
- Dose: 20 mg PO bid x14 days; Info: give w/ amoxicillin 1 g PO tid; dosing may vary; do not cut/crush/chew tab; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool
renal dosing
- [erosive esophagitis initial tx]
- eGFR <30: 10 mg qd
- HD/PD: not defined
- [H. pylori infection]
- eGFR <30: avoid use
- HD/PD: not defined
- [all other indications]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [erosive esophagitis initial tx]
- Child-Pugh Class B or C: 10 mg qd
- [H. pylori infection]
- Child-Pugh Class B or C: avoid use
- [all other indications]
- hepatic impairment: no adjustment
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.