Ebglyss (lebrikizumab-lbkz)

Adult Dosing .

Dosage forms:  INJ (pen): 250 mg per injection; INJ (pre-filled syringe): 250 mg per 2 mL

Special Note

[formulation clarification]

Info: nonproprietary name = lebrikizumab-lbkz

atopic dermatitis, moderate-severe

[>40 kg]

Dose: 250 mg SC q4wk; Start: 500 mg SC x1 on wk 0, 2, then 250 mg SC q2wk for at least 16 wk, then 250 mg SC q4wk

renal dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ (pen): 250 mg per injection; INJ (pre-filled syringe): 250 mg per 2 mL

Special Note

[formulation clarification]

Info: nonproprietary name = lebrikizumab-lbkz

atopic dermatitis, moderate-severe

[12 yo and older, >40 kg]

Dose: 250 mg SC q4wk; Start: 500 mg SC x1 on wk 0, 2, then 250 mg SC q2wk for at least 16 wk, then 250 mg SC q4wk

renal dosing

[see below]

mild-moderate impairment: no adjustment; severe impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]