milrinone

Adult Dosing .

Dosage forms:  INJ

heart failure, acute decompensated

[0.125-0.75 mcg/kg/min IV]

Max: 0.75 mcg/kg/min; Info: use lowest effective dose, shortest effective tx duration

post-resuscitation stabilization (off-label)

[0.375-0.75 mcg/kg/min IV]

Start: 50 mcg/kg/dose IV x1; Info: refer to ACLS guidelines

renal dosing

[adjust infusion rate]

CrCl 50: 0.43 mcg/kg/min; CrCl 40: 0.38 mcg/kg/min; CrCl 30: 0.33 mcg/kg/min; CrCl 20: 0.28 mcg/kg/min; CrCl 10: 0.23 mcg/kg/min; CrCl 5: 0.20 mcg/kg/min

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

post-resuscitation stabilization (off-label)

[0.25-0.75 mcg/kg/min IV/IO]

Start: 50 mcg/kg/dose IV/IO x1; Info: refer to PALS guidelines

renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: not defined

hepatic dosing

[not defined]