adenosine

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 6 mg per 2 mL, 12 mg per 4 mL; INJ (vial): 6 mg per 2 mL, 12 mg per 4 mL, 60 mg per 20 mL, 90 mg per 30 mL

PSVT conversion

[6 mg IV x1, then 12 mg IV q1-2min x1-2 prn]

Info: give all doses rapid IV push over 1-3sec; decr. initial dose to 3 mg IV x1 if cardiac transplant pt or if admin. via central venous access

ACLS, tachycardia

[6 mg IV x1, then 12 mg IV q1-2min x1 prn]

Info: for pts w/ unstable regular narrow-complex awaiting cardioversion, stable regular monomorphic wide-complex, or stable regular monomorphic narrow-complex tachycardia; give all doses rapid IV push over 1-3sec; decr. initial dose to 3 mg IV x1 if cardiac transplant pt or if admin. via central venous access; see ACLS: Tachycardia table

myocardial perfusion imaging

[140 mcg/kg/min IV x6min]

Info: for pts unable to undergo adequate exercise stress; for use w/ thallium-201

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ (pre-filled syringe): 6 mg per 2 mL, 12 mg per 4 mL; INJ (vial): 6 mg per 2 mL, 12 mg per 4 mL, 60 mg per 20 mL, 90 mg per 30 mL

PSVT conversion

[<50 kg]

Dose: 0.05-0.1 mg/kg/dose IV x1, then incr. by 0.05-0.1 mg/kg/dose IV q1-2min prn; Max: 0.3 mg/kg/dose up to 12 mg/dose; Info: give all doses rapid IV push over 1-3sec; decr. initial dose if cardiac transplant pt or if admin. via central venous access

[>50 kg]

Dose: 6 mg IV x1, then 12 mg IV q1-2min x1-2 doses prn; Info: give all doses rapid IV push over 1-3sec; decr. initial dose if cardiac transplant pt or if admin. via central venous access

PALS, tachycardia

[0.1 mg/kg/dose IV/IO x1, then 0.2 mg/kg/dose IV/IO x1 prn]

Max: 6 mg initial dose, 12 mg subsequent dose; Info: for pts w/ stable regular narrow-complex, unstable regular narrow-complex awaiting cardioversion, or stable regular monomorphic wide-complex tachycardia; give all doses rapid IV push over 1-3sec; decr. initial dose if cardiac transplant pt or if admin. via central venous access; see PALS: Tachycardia table

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]