Caverject

Adult Dosing .

Dosage forms:  INJ (pre-filled syringe): 10 mcg per 0.5 mL, 20 mcg per 0.5 mL; INJ (vial): 20 mcg per mL, 40 mcg per mL

erectile dysfxn

[vasculogenic, psychogenic, or mixed etiology]

Dose: individualize dose intracavernously up to 3x/wk prn; Start: 2.5 mcg intracavernously x1, then w/in 1h may give additional 2.5 mcg intracavernously x1 if partial response, then if additional titration needed, may incr. dose by 5-10 mcg/dose given at least 24h apart until optimal response achieved; Max: 2 doses/24h during initial titration, then 1 dose/24h; 60 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

[pure neurologic etiology]

Dose: individualize dose intracavernously up to 3x/wk prn; Start: 1.25 mcg intracavernously x1, then w/in 1h may give additional 1.25 mcg intracavernously x1 if partial response, then if additional titration needed, may give 5 mcg intracavernously x1 at least 24h later, then may repeat titration until optimal response achieved; Max: 2 doses/24h during initial titration, then 1 dose/24h; 60 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

erection induction, erectile dysfxn diagnostic studies

[individualize dose intracavernously x1]

Start: 2.5 mcg intracavernously x1, then w/in 1h may give additional 2.5 mcg intracavernously x1 if partial response, then if additional titration needed, may incr. dose by 5-10 mcg/dose at least 24h apart until optimal response achieved; Max: 2 doses/24h during initial titration, then 1 dose/24h; 60 mcg/dose; Info: duration of erection not to exceed 1h; use lowest effective dose

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[not defined]

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.